3D-Locating Improves Postoperative Evaluation of Implantable Collamer Lens 

A 3D-locating approach can accurately characterize the location of an implantable collamer lens (ICL) in the anterior segment of patients with myopia after implantation, according to research published in the American Journal of Ophthalmology. 

Researchers conducted a cross-sectional study to describe the location of the ICL in the posterior ocular chamber of adult patients with myopia using a 3D-locating method that pairs 360-degree swept-source optical coherence tomography (SS-OCT) with deep-learning artificial intelligence. Patients underwent ICL implantation between June 2021 and December 2021 at a single center.

The researchers used the 3D-locating method to create visualization models before and after mydriasis in 32 eyes of 20 patients (mean age, 25.90±6.36 years; 11 women, 9 men) and evaluated various parameters, including ICL-lens volume (ILV), the tilt of the ICL and crystalline lens, the vault distribution index, and topographic maps, to characterize the location of the ICL. They compared the parameter values between the nonmydriasis and post-mydriasis conditions.

The study shows no significant difference from baseline in the 3D central vault (mean, 595.49±212.35 μm vs 587.15±162.00 μm; P =.994) and a decrease of 0.85 mm² in the 5 mm ILV (mean, 11.51±4.07 vs 10.65±2.84 mm²; P =.016), and an increase 0.09 in the vault distribution index (0.79 vs 0.93; P =.001) after mydriasis. 

Using the 3D-locating technique, the researchers also identified the tilt in the ICL and crystalline lens both before and after mydriasis (nonmydriasis: ICL total tilt, 3.78±1.85°; lens total tilt, 4.03 ±1.53°; postmydriasis: ICL total tilt, 3.84±1.56°; lens total tilt, 4.09±1.64°). 

“The use of SS-OCT scans and 3D imaging improves patient comfort and clinical follow-up efficiency. It also allows physicians to assess the ICL’s position in the anterior segment more precisely,” explain the reserachers.

Limitations of the study included the small sample size and evaluation only in the ICL optical zone.