Bilateral implantation of a new nondiffractive wavefront-shaping extended depth-of-focus (EDOF) intraocular lens (IOL) provides good visual performance at far and intermediate distance and functional near visual acuity (VA), according to research published in the Journal of Cataract & Refractive Surgery.
The prospective, single-arm, single-center study was conducted at the Department of Ophthalmology, Goethe University in Frankfurt, Germany. The researchers evaluated visual performance and patient-reported outcomes of patients who underwent bilateral femtosecond laser–assisted phacoemulsification and implantation of the nondiffractive wavefront-shaping EDOF IOL (AcrySof IQ Vivity, Alcon Research) between November 2019 and February 2021.
The main outcome measures were monocular and binocular uncorrected (UCVA), distance-corrected visual acuity (DCVA), refractive outcome, defocus curve, contrast sensitivity (CS), and quality of vision (based upon a questionnaire on optical phenomena and spectacle independence) at 3 months after surgery.
The study included 32 eyes of 16 patients (mean age, 68 years; range, 54-78; and 56% men, 44% women). The mean lens power was +20.69 ± 2.220 D (range 17.0-25.0), and the mean target refraction was 0.17 ± 0.154 D.
The mean spherical equivalent changed from -0.38 ± 3.114 D (range, -6.25 to 3.75) preoperatively to -0.16 ± 0.356 D (-0.88 to 0.50) postoperatively. After 3 months, the mean binocular UCVA was 0.01 ± 0.05 logMAR at 4 m, 0.05 ± 0.05 logMAR at 80 cm, and 0.07 ± 0.06 logMAR at 66 cm, and 0.25 ± 0.11 logMAR at 40 cm; CS was 1.25 ± 0.41 logCS (photopic), 0.96 ± 0.24 logCS (mesopic), and 0.93 ± 0.24 (mesopic + glare). The questionnaire revealed that 88% of patients would choose the same lens, and 63% of patients reported no optical phenomena.
“This new nondiffractive EDoF IOL is able to provide excellent VA for far and intermediate without compromising on near VA while causing only a low amount of optical phenomena,” concluded the researchers.
Limitations of the study included the relatively small sample size, the use of an unvalidated questionnaire, and a short follow-up period.
Disclosure: Some study authors declared affiliations with biotech, pharmaceutical, and/or device companies. Please see the original reference for a full list of authors’ disclosures.
Kohnen T, Petermann K, Böhm M, et al. Nondiffractive wavefront-shaping extended depth-of-focus intraocular lens: visual performance and patient-reported outcomes. J Cataract Refract Surg. 2022;48(2):144-150. doi:10.1097/j.jcrs.0000000000000826