Canaloplasty Technique Lowers IOP, With or Without Phaco

Performing surgery
Doctor performing eye surgery in modern clinic
A study shows the effect of ab-interno canaloplasty with iTrack for patients with glaucoma.

This article is part of Ophthalmology Advisor’s conference coverage from the 2021 meeting of the American Academy of Ophthalmology, held in New Orleans from November 12 to 15, 2021. The team at Ophthalmology Advisor will be reporting on a variety of the research presented by the ophthalmology experts at the AAO. Check back for more from the AAO 2021 Meeting.


Ab-interno canaloplasty with iTrack (ABiC) led to a decrease in intraocular pressure (IOP) when performed either alone or in combination with cataract surgery, according to results presented at the American Academy of Ophthalmology 2021 annual meeting held in New Orleans from November 12 to November 15. The procedure also reduced the amount of glaucoma medication needed, presenters said.

Researchers sought to assess the clinical outcomes associated with ABiC as a stand-alone procedure or with the addition of phacoemulsification (ABiC+phaco) spanning a 2-year period.  

The nonrandomized, single center study included 869 eyes from adult patients with controlled and uncontrolled open-angle glaucoma and no previous glaucoma surgeries, with 275 in the ABiC group and 594 in the ABiC + phaco group. 

The average baseline IOP was 21.2±6.8 mmHg for the ABiC group and 18.0±6.5 mmHg for the ABiC+phaco group. Glaucoma medication numbers were 2.1±1.2 (ABiC) and 1.7±1.1 (ABiC+phaco). After 2 years, the average IOP  was reduced to 15.6±3.7 mmHg (n=60) in the ABiC group and 15.1±4.3 mmHg (n=136) in the ABiC + phaco group. At 24 months, the mean number of medications was reduced to 1.20±1.2 (ABiC) and 0.70±1.0 (ABiC+phaco). 

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Khaimi MA, Ding K. Ab interno canaloplasty stand-alone vs. combined with cataract surgery: 24 month outcomes in 800+ eyes. Paper presented at: American Academy of Ophthalmology 2021 Annual Meeting; November 12-15, 2021; New Orleans. Abstract PA002.