Neovascular AMD Patients Experience More Complications After Cataract Surgery

Doctor performing eye surgery in modern clinic
Researchers note a higher rate of posterior capsule rupture and dropped lens fragments in some patients.

The following article is a part of conference coverage from the American Academy of Ophthalmology 2020, being held virtually from November 13 to 15, 2020. The team at Ophthalmology Advisor will be reporting on the latest news and research conducted by leading experts in ophthalmology. Check back for more from the AAO 2020.

Surgeons performing cataract surgery need to account for the presence of neovascular age-related macular degeneration (nAMD), according to researchers presenting at the American Academy of Ophthalmology 2020 meeting, due to this class of patient’s proclivity for both better visual acuity after cataract surgery and risk of some complications.

The investigators set out to compare visual outcomes and the rate of intraoperative complications in cataract surgery patients with and without nAMD. They found that nearly 30% of the 906 nAMD eyes that underwent cataract surgery had improvement in acuity of approximately 0.2 logMAR at their 12-week follow-up. 

However, the patients with nAMD did demonstrate a higher rate of posterior capsule rupture, 2.9%, compared with the non-nAMD group 1.1%, (P <.0001). They also experienced more cases of dropped lens fragments (0.6% vs 0.1%; P <.0001). 

The investigators also found that nAMD eyes were able to resume treatment with intravitreal injections within 3 months of the surgery, the study says.

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Siddiqui M, Ahmad K, Soliman M, Sallam A. Visual outcomes and intraoperative complications of cataract surgery in nAMD: a multicenter database study. Presented at: American Academy of Ophthalmology 2020 Annual Meeting; November 13-15, 2020. Abstract PO428.