Corneal Remodeling Shows Long-Term Safety, Effectiveness

The cornea plastic.
A 6-year study shows the technique, which is both safe and effective, can treat corneal ectasia.

The following article is a part of conference coverage from the American Academy of Ophthalmology 2020, being held virtually from November 13 to 15, 2020. The team at Ophthalmology Advisor will be reporting on the latest news and research conducted by leading experts in ophthalmology. Check back for more from the AAO 2020.

Corneal remodeling is a safe, effective technique to treat corneal ectasia, producing favorable outcomes for patients who undergo this procedure. Data from a long-term follow-up study were presented at the American Academy of Ophthalmology 2020 Annual Meeting, held virtually November 13 to 15, 2020. 

In order to evaluate the 6-year outcomes of a femtosecond-assisted technique for the treatment of corneal ectasia, researchers evaluated 131 cases (patient age: 36.28 ± 15.19 years) of corneal remodeling. In each case, anesthetic drops were applied, and a femtosecond laser was used to perform an ablation (8 mm, 270-degree or 360-degree keratectomy). Interrupted stitches were used to suture the resection. 

Postoperative 6-year uncorrected distance visual acuity was approximately 0.47; corrected distance visual acuity changed from 0.26 (± 0.14) to 0.81 (± 0.16). Sphere change improved, from -3.69 (± 3.51) to -0.21 (± 2.21), and 100% of cases transitioned from preoperative against-the-rule or oblique astigmatism to postoperative presentation of with-the-rule astigmatism. 

Following photorefractive keratectomy procedures conducted in 40 patients, an uncorrected distance visual acuity of 20/30 or better was achieved. All patients gained at least 1 line of corrected distance visual acuity, with 45% of patients gaining 4 to 6 lines. 

Finally, postoperative coma aberration decreased up to 80%.

“Corneal remodeling is a safe technique,” the researchers concluded. “It produces a new corneal profile, and it allows surgeons to perform complementary procedures.” 


Carriazo CC, Cosentino MJ. Corneal remodeling, a new technique to treat keratoconus: Six-year follow-up. Presented at: American Academy of Ophthalmology 2020 Annual Meeting; November 13-15, 2020. Abstract RP30065769

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